Hikmet Hakan Aydin, M.D.

Professor and Chair, Department of Medical Biochemistry

Chair of the Department of Medical Biochemistry at the Ege University Faculty of Medicine. Research and clinical interests encompass the molecular biology of aging, clinical enzymology, and the application of multi-omic biomarker profiling in precision medicine.

M.D. NACB Fellow EuSpLM Specialist B.A. Business Administration
Contact Info Research Portfolio
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Primary Research Areas

Biology of Aging

Investigating mitochondrial DNA sequence variations and transcriptomic profiles to elucidate the cellular mechanisms underlying human longevity and the biology of aging.

Precision Medicine

Applying molecular biomarker profiling, gene expression analysis, and targeted genomic approaches to develop tailored therapeutic strategies for specific clinical cohorts.

Clinical Diagnostics

Developing, standardizing, and evaluating high-complexity clinical biochemical assays and diagnostic biomarkers for translational applications.

Academic Leadership

2023 – Present

Chair

Ege University Faculty of Medicine, Department of Medical Biochemistry

Directing departmental research initiatives, graduate medical education curricula, and clinical diagnostic operations (Appointed Professor, 2007).

2016 – 2017

Dean & Hospital President/CEO

Ege University Faculty of Medicine & Teaching Hospital

Directed academic governance, clinical operations, quality assurance, and institutional strategy for the academic medical center.

2016 – 2017

Director

Ege University Science and Technology Centre

Oversaw interdisciplinary research infrastructure and university-industry technology transfer initiatives.

2008 – 2016

Advisory Committee Member

Turkish Ministry of Health

Contributed to national health policies, regulatory guidelines, and ethical review standards for clinical trials and cancer research on the National Cancer Advisory Committee and Clinical Researches Advisory Committee.

Selected Recent Publications

Paired copy number variation analysis in siblings discordant for familial Parkinson’s disease
Atay S, Acarer A, Ak H, Colakoglu Z, Aydin HH (2025). Annals of Clinical Biochemistry, 62(5):366-376.
Extracellular microRNAs: key players to explore the outcomes of in vitro fertilization
Khan HL, Bhatti S, Abbas S... Aydin HH, Kalyan EY (2021). Reproductive Biology and Endocrinology, 19(1):72.
Evaluation of complement system proteins C3a, C5a and C6 in patients of endometriosis
Karadadas E, Hortu I, Ak H, Ergenoglu AM, Karadadas N, Aydin HH (2020). Clinical Biochemistry, 81:15-19.
Is overactive bladder microvasculature disease a component of systemic atheroscleorosis?
Yeniel AO, Ergenoglu AM, Meseri R... Aydin HH, et al. (2018). Neurourology and Urodynamics, 37(4):1372-1379.
R132H mutation in IDH1 gene is associated with increased tumor HIF1-alpha and serum VEGF levels in primary glioblastoma multiforme
Yalaza C, Ak H, Cagli MS, Ozgiray E, Atay S, Aydin HH (2017). Annals of Clinical & Laboratory Science, 47(3):362-364.

Contact Information

Available for academic collaboration, scientific consultation, and guest lectureships. Please utilize the institutional contact details below for inquiries.

Academic Address Ege University Faculty of Medicine
Department of Medical Biochemistry
Bornova, İzmir 35100, Türkiye
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Email hakan.aydin@ege.edu.tr
hhakan.aydin@gmail.com
Department Office +90 232 390 3699
Department Fax +90 232 373 7034